Difference: Covid19 Third Dose vs Booster Shot Vaccines
General public wants to understand what is the difference between third Covid dose and booster shots. FDA has recently approved third doses and booster shots of the Pfizer vaccine for COVID-19.
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FDA’s Update on Moderna, Pfizer & J&J Covid Vaccines
Those who got Moderna or Johnson & Johnson’s (J&J) vaccine must wait to see if the Food and Drug Administration (FDA) will authorize one. The FDA will be checking the possibility of a Moderna booster and a J&J booster in coming days. They’ll be considering boosters for both shots for fully vaccinated people who are aged 18 or older.
Some people are getting their Coronavirus vaccine boosters and others are getting their third shot. While they may seem like the same thing, they actually aren’t.
CDC Endorsement of Pfizer Covid Vaccine
The Centers for Disease and Control and Prevention (CDC) endorsed booster shots of Pfizer’s COVID-19 vaccine for vulnerable and older Americans, which are not to be confused with third doses of the vaccine.

Difference: Covid19 Third Dose vs Booster Shot Vaccines
Walgreen’s chief medical officer, Dr. Kevin Ban, helped outline the difference between a booster shot and a third shot of the vaccine on the 3rd hour as Walgreen’s prepares to offer booster shots of the Pfizer-BioNTech vaccine to those who are eligible.
“The third shot is what’s referred to as the extra vaccine for immunocompromised people, as opposed to the booster, which is just given as an extra shot either because you are older or have a chronic medical condition,” said Dr. Joseph Kontra, with Lancaster General Health.
What is Booster Dose
A booster is also a third dose, but it’s used when help is needed to prolong protective immunity in someone who responded fully after the first two doses but there’s evidence that protection is waning after some time. In essence, a “top-up” of a person’s effective immune response to the first vaccine series.
What is Third Dose
The term “third shot” is used to describe a third dose that’s needed when a person’s immune response likely hasn’t responded fully to the vaccine after the first doses — such is the case for people who have undergone solid organ transplants and others who are seriously immunocompromised.
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